python - Apache stops serving request

I am running django with mod_wsgi and every thing works fine most of the time but at times I observe that all of sudden Apache stops serving any requests, monitoring service on server says httpd is still running but requests take too long and fails with premature script headers.

I am running this setup on RHEL with python 2.6

wsgi directives

WSGISocketPrefix /var/run/wsgi
WSGIScriptAlias / /srv/bin/bootstrap.wsgi
WSGIDaemonProcess bstapp user=django-user group=django-user
WSGIProcessGroup bstapp